Sıra | DOSYA ADI | Format | Bağlantı |
---|---|---|---|
01. | Yaşam Süresi Değerlendirmeleri | ppt | Sunumu İndir |
Transkript
1Yaşam Süresi DeğerlendirmeleriTÜRK TORAKS DERNEĞİ14. YILLIK KONGRESİ16 Nisan 2011Doç. Dr. Mutlu Hayran, Hacettepe Üniversitesi Onkoloji Entsitüsü, Prevantif Onkoloji ABD
Çıkar Çatışması Bulunmamaktadır.2
“Delik Boru” Taranamayan ya da Ön Taramayı GeçemeyenKriterleri SağlamayanOlur VermeyenÇalışmadan ÇıkanÇalışma EvreniAnaliz Grubu
Hasta Alım İşlemlerine Göre Hasta Sayıları1500300150 8002004006008001000120014001600Birey sayısıİ lk duyuruya cevap veren Klinik taramasına gelenÇalışmaya alınan Değerlendirmeye alınan
PARAMETRE VE İSTATİSTİK Parametre: Bir toplum/topluluk ile ilişkili değer ya da tanım İstatistik: Toplumdan alınmış bir örnekten hesaplanan değer ya da tanımPİ İ
Tip-1 ve Tip-2 hataların ortaya çıkma şekilleri Gerçek HayatFark ya da İlişki Var Fark ya da İlişki YokÇalışmaİçindeBulunan SonuçFark ya da İlişki BulunduÇalışma başarılıÇalışmada Tip-I hata yapılmışFark ya da İlişki BulunmadıÇalışmada Tip-2 hata yapılmışÇalışma başarılı
ÇALIŞMANIN GÜCÜ VE GÜVEN ARALIKLARI TİP-1 HATA TİP-2 HATAGüven AralıklarıÇalışmanın Gücü
8Kategorik Değişken (Dikotom)Kemik ağrısıOran (Sayı, %)Oran (Sayı, %)
9Kategorik Değişken (Nominal)Yattığı ServisG. Dahiliye G. Cerrahi Yoğun Bak.Oran (Sayı, %)Oran (Sayı, %)
10Kategorik Değişken (Ordinal)Advers Olay ŞiddetiOran (Sayı, %)Oran (Sayı, %)Ortanca (Min-Maks)Ortanca (Min-Maks)43413211123344
11Sayısal Değişken – 1Ortalama (SD)Ortalama (SD)
12Sayısal Değişken – 2Ortanca (Min-Maks)Ortanca (Min-Maks)Ortanca (IQR)Ortanca (IQR)En düşük ve En yüksek 4’te 1’i atıldıktan sonraminimum ve maksimum
13Sağkalım AnaliziTedavi SonuçA ÖldüA ÖldüA HayattaA ÖldüB HayattaB HayattaB HayattaB ÖldüTakip Süresi45 ay43 ay29 ay31 ay19 ay21 ay27 ay25 ay
14Tedavi ATedavi BÇALIŞMAGRUBUÖldüÖldüKurtulduKurtulduOranların KarşılaştırmasıBu tedavi sonucunda kurtulduğu kesin.
15Tedavi ATedavi BÇALIŞMAGRUBUÖldüÖldüYaşıyorYaşıyorSağkalım Analizi
TanıKayıt Tx CR Tox ProgEx/LFUTTRDCRTTFTTPOSYaşam analizi süre tanımları
17TIME = (VIS1DATE-LASTDATE) / 86400 / 365.25 *12SüreSon Durum
18RRRRRRRRRRemisyonRelapsÖldüYaşıyor12345672006, Ekim 2011, Ocak
19 İzlem sürelerinin belirli aralıklar halinde kategorize edilmesi gerekir. Yalnız tek etkenin sağkalım üzerine etkileri analiz edilebilir. Toplum tabanlı çalışmalarda yüksek sayılarda tercih edilirYaşam-tablosu analizi
20BaşlayanTakipten çıkanRisk altındaki grupÖlümÖlenlerin oranıSağkalanların oranıKümülatif sağkalım7 7 4 30 2 0 17 6 4 2.50 1 1 10.00% 16.67% 25.00% 40.00%100.00% 83.33% 75.00% 60.00%100.00% 83.33% 62.50% 37.50%R RRemisyon RelapsÖldü YaşıyorR R1 R2 R R34 R5 R6712 24 36 48100,0 83,3 75,0 60,0100,0 83,3 62,5 37,5
21 İzlem sürelerinin kategorize edilmesi gerekmez. Birden çok etkenin sağkalım üzerine etkileri analiz edilebilir (Log rank testi). Sayısal (kategorik olmayan) değişkenlerin (yaş vb.) etkileri analiz edilemez.Kaplan-Meier sağkalım analizi
22Sağkalım grafiğiMedyan sağkalım süresi72 ay5-yıllık yaşam hızı ~53%1-yıllık yaşam hızı ~83%
23Survival Table3.367 Alive . . 0 4153.567 Alive . . 0 4143.567 Alive . . 0 4133.833 Alive . . 0 4124.167 Alive . . 0 4114.367 Alive . . 0 4104.733 Alive . . 0 4094.867 Alive . . 0 4085.800 Alive . . 0 4075.933 Alive . . 0 4066.067 Alive . . 0 4056.367 Alive . . 0 4046.567 Alive . . 0 4036.867 Alive . . 0 4027.067 Alive . . 0 4017.167 Alive . . 0 4007.300 Alive . . 0 3997.300 Alive . . 0 3987.367 Alive . . 0 3978.167 Alive . . 0 3968.167 Alive . . 0 3958.233 Alive . . 0 3948.667 Alive . . 0 3938.867 Alive . . 0 3929.233 Alive . . 0 3919.300 Alive . . 0 3909.800 Alive . . 0 3899.900 Alive . . 0 38810.233 Alive . . 0 38710.567 Alive . . 0 38610.600 Alive . . 0 38510.633 Alive . . 0 38410.933 Alive . . 0 38310.933 Alive . . 0 38211.000 Alive . . 0 38111.000 Alive . . 0 38011.033 Ex .997 .003 1 37911.200 Alive . . 1 37811.667 Alive . . 1 37711.733 Alive . . 1 37612.000 Alive . . 1 37512.200 Ex .995 .004 2 37412.433 Ex .992 .005 3 37312.567 Alive . . 3 37213.067 Alive . . 3 37113.067 Alive . . 3 37013.367 Alive . . 3 36913.600 Alive . . 3 36813.767 Alive . . 3 36713.933 Alive . . 3 36614.133 Alive . . 3 36514.400 Alive . . 3 36414.733 Alive . . 3 36315.133 Alive . . 3 36215.600 Alive . . 3 36115.667 Alive . . 3 36016.100 Alive . . 3 35916.567 Alive . . 3 35816.700 Alive . . 3 35717.133 Ex .989 .005 4 35617.133 Alive . . 4 35517.200 Alive . . 4 35417.533 Alive . . 4 35317.767 Alive . . 4 35217.800 Alive . . 4 35118.100 Ex .986 .006 5 35018.300 Alive . . 5 34918.500 Alive . . 5 34818.500 Alive . . 5 34718.667 Alive . . 5 34618.667 Alive . . 5 34518.700 Alive . . 5 34418.767 Ex .984 .007 6 34318.867 Alive . . 6 34219.133 Alive . . 6 34119.467 Alive . . 6 34019.767 Alive . . 6 33919.833 Ex .981 .007 7 33819.867 Alive . . 7 33720.267 Alive . . 7 33620.467 Alive . . 7 33520.567 Alive . . 7 33420.733 Alive . . 7 33320.867 Alive . . 7 33221.000 Alive . . 7 33121.233 Alive . . 7 33021.767 Ex .978 .008 8 32921.967 Alive . . 8 32822.233 Alive . . 8 32722.367 Alive . . 8 32622.500 Alive . . 8 32522.500 Alive . . 8 32422.533 Alive . . 8 32322.733 Alive . . 8 32222.867 Alive . . 8 32122.900 Alive . . 8 32022.933 Alive . . 8 31923.400 Alive . . 8 31823.567 Ex .975 .008 9 31723.767 Alive . . 9 31624.000 Alive . . 9 31524.200 Alive . . 9 31424.333 Ex .972 .009 10 31324.333 Alive . . 10 31224.633 Ex .968 .009 11 31124.700 Alive . . 11 31025.233 Ex .965 .010 12 30925.367 Ex .962 .010 13 30825.400 Alive . . 13 30725.433 Ex .959 .011 14 30625.700 Alive . . 14 30525.833 Alive . . 14 30425.933 Alive . . 14 30326.133 Ex .956 .011 15 30226.167 Alive . . 15 30126.300 Alive . . 15 30026.633 Alive . . 15 29926.933 Alive . . 15 29827.400 Alive . . 15 29727.633 Ex .953 .012 16 29627.733 Alive . . 16 29528.067 Alive . . 16 29428.133 Alive . . 16 29328.333 Ex .949 .012 17 29229.533 Ex .946 .012 18 29129.567 Ex .943 .013 19 29030.400 Alive . . 19 28930.933 Alive . . 19 28831.167 Alive . . 19 28731.200 Alive . . 19 28631.367 Alive . . 19 28531.533 Ex .940 .013 20 28431.567 Alive . . 20 28331.733 Alive . . 20 28232.100 Alive . . 20 28132.367 Alive . . 20 28032.667 Alive . . 20 27932.967 Alive . . 20 27833.700 Alive . . 20 27733.833 Alive . . 20 27634.067 Alive . . 20 27534.400 Alive . . 20 27434.600 Alive . . 20 27334.767 Alive . . 20 27234.833 Alive . . 20 27134.900 Alive . . 20 27035.233 Alive . . 20 26935.367 Alive . . 20 26835.400 Alive . . 20 26735.667 Alive . . 20 26635.700 Alive . . 20 26535.733 Alive . . 20 26436.200 Alive . . 20 26336.333 Alive . . 20 26236.367 Alive . . 20 26136.500 Alive . . 20 26036.600 Alive . . 20 25936.867 Ex .936 .014 21 25836.933 Alive . . 21 25736.967 Alive . . 21 25637.067 Alive . . 21 25537.067 Alive . . 21 25437.133 Alive . . 21 25337.467 Alive . . 21 25237.700 Ex .932 .014 22 25138.033 Alive . . 22 25038.333 Alive . . 22 24938.400 Alive . . 22 24838.867 Alive . . 22 24738.967 Alive . . 22 24639.500 Alive . . 22 24539.833 Alive . . 22 24440.100 Ex .928 .014 23 24340.300 Alive . . 23 24240.567 Alive . . 23 24140.700 Alive . . 23 24041.167 Alive . . 23 23941.267 Ex .925 .015 24 23841.367 Alive . . 24 23741.400 Ex .921 .015 25 23641.433 Alive . . 25 23541.533 Ex .917 .016 26 23441.733 Alive . . 26 23341.800 Alive . . 26 23241.900 Alive . . 26 23142.233 Ex .913 .016 27 23042.300 Alive . . 27 22942.333 Alive . . 27 22842.867 Alive . . 27 22742.933 Alive . . 27 22642.967 Ex .909 .017 28 22543.400 Alive . . 28 22443.500 Ex .905 .017 29 22343.567 Alive . . 29 22243.600 Alive . . 29 22143.633 Alive . . 29 22043.700 Alive . . 29 21943.867 Alive . . 29 21843.867 Alive . . 29 21744.367 Alive . . 29 21644.767 Alive . . 29 21545.200 Alive . . 29 21445.300 Ex .900 .017 30 21345.567 Alive . . 30 21245.933 Alive . . 30 21146.367 Alive . . 30 21046.467 Ex .896 .018 31 20946.600 Alive . . 31 20846.600 Alive . . 31 20746.833 Alive . . 31 20647.000 Alive . . 31 20547.067 Alive . . 31 20447.267 Alive . . 31 20347.733 Alive . . 31 20247.833 Alive . . 31 20147.833 Alive . . 31 20047.867 Alive . . 31 19948.100 Alive . . 31 19848.167 Alive . . 31 19748.533 Alive . . 31 19648.533 Alive . . 31 19548.667 Alive . . 31 19448.833 Alive . . 31 19348.933 Alive . . 31 19249.367 Alive . . 31 19149.533 Alive . . 31 19050.067 Alive . . 31 18950.133 Alive . . 31 18850.367 Alive . . 31 18750.567 Alive . . 31 18650.733 Alive . . 31 18550.833 Alive . . 31 18450.867 Alive . . 31 18350.900 Alive . . 31 18251.467 Alive . . 31 18152.233 Alive . . 31 18052.433 Alive . . 31 17952.933 Alive . . 31 17853.000 Alive . . 31 17753.133 Alive . . 31 17653.500 Ex .891 .019 32 17553.667 Alive . . 32 17453.667 Alive . . 32 17353.667 Alive . . 32 17253.700 Alive . . 32 17154.267 Alive . . 32 17054.333 Alive . . 32 16954.567 Alive . . 32 16854.600 Ex .886 .019 33 16754.833 Alive . . 33 16654.833 Alive . . 33 16554.900 Alive . . 33 16455.333 Alive . . 33 16355.433 Alive . . 33 16256.433 Alive . . 33 16156.467 Alive . . 33 16056.567 Ex .880 .020 34 15956.767 Alive . . 34 15857.033 Alive . . 34 15757.300 Alive . . 34 15657.400 Alive . . 34 15557.467 Alive . . 34 15458.067 Alive . . 34 15358.200 Alive . . 34 15258.367 Alive . . 34 15159.033 Ex .874 .021 35 15059.267 Alive . . 35 14959.500 Alive . . 35 14860.067 Alive . . 35 14760.200 Alive . . 35 14660.333 Alive . . 35 14560.500 Alive . . 35 14460.767 Alive . . 35 14360.867 Alive . . 35 14261.133 Alive . . 35 14161.133 Alive . . 35 14061.200 Alive . . 35 13961.267 Alive . . 35 13861.367 Alive . . 35 13762.033 Alive . . 35 13662.167 Alive . . 35 13562.267 Alive . . 35 13462.533 Ex .868 .021 36 13362.533 Alive . . 36 13262.733 Alive . . 36 13162.800 Alive . . 36 13062.833 Alive . . 36 12963.300 Alive . . 36 12863.633 Alive . . 36 12763.700 Alive . . 36 12663.800 Alive . . 36 12563.900 Alive . . 36 12464.167 Alive . . 36 12364.267 Ex .861 .022 37 12265.133 Alive . . 37 12166.533 Alive . . 37 12066.700 Alive . . 37 11966.767 Alive . . 37 11866.800 Ex .854 .023 38 11766.967 Alive . . 38 11666.967 Alive . . 38 11567.767 Alive . . 38 11467.767 Alive . . 38 11368.167 Alive . . 38 11268.367 Alive . . 38 11168.567 Alive . . 38 11068.833 Alive . . 38 10969.100 Alive . . 38 10869.333 Alive . . 38 10769.467 Alive . . 38 10669.500 Alive . . 38 10570.167 Alive . . 38 10471.200 Alive . . 38 10371.367 Alive . . 38 10271.700 Alive . . 38 10171.767 Alive . . 38 10072.633 Alive . . 38 9973.033 Alive . . 38 9873.033 Alive . . 38 9773.467 Alive . . 38 9673.533 Alive . . 38 9574.633 Alive . . 38 9474.733 Alive . . 38 9374.967 Alive . . 38 9275.667 Alive . . 38 9176.133 Ex .844 .025 39 9076.200 Alive . . 39 8976.233 Alive . . 39 8876.500 Alive . . 39 8776.900 Alive . . 39 8677.900 Alive . . 39 8578.200 Alive . . 39 8478.667 Alive . . 39 8378.867 Alive . . 39 8278.867 Alive . . 39 8178.933 Alive . . 39 8079.333 Alive . . 39 7979.567 Alive . . 39 7880.000 Alive . . 39 7780.300 Alive . . 39 7680.400 Alive . . 39 7581.133 Alive . . 39 7481.167 Alive . . 39 7381.233 Alive . . 39 7281.367 Alive . . 39 7181.467 Alive . . 39 7081.767 Alive . . 39 6981.833 Alive . . 39 6882.667 Alive . . 39 6782.667 Alive . . 39 6682.667 Alive . . 39 6583.033 Alive . . 39 6483.267 Ex .831 .028 40 6383.533 Alive . . 40 6283.867 Alive . . 40 6184.200 Alive . . 40 6084.633 Alive . . 40 5984.667 Alive . . 40 5884.800 Alive . . 40 5784.933 Alive . . 40 5685.167 Alive . . 40 5585.567 Alive . . 40 5486.200 Alive . . 40 5387.000 Alive . . 40 5287.067 Alive . . 40 5187.133 Alive . . 40 5087.500 Alive . . 40 4987.900 Alive . . 40 4888.733 Alive . . 40 4789.133 Alive . . 40 4689.400 Alive . . 40 4589.967 Alive . . 40 4490.167 Alive . . 40 4390.333 Alive . . 40 4290.933 Alive . . 40 4191.167 Alive . . 40 4091.933 Alive . . 40 3993.300 Alive . . 40 3894.167 Alive . . 40 3794.333 Ex .808 .035 41 3696.400 Alive . . 41 3596.400 Alive . . 41 3497.100 Alive . . 41 3397.400 Alive . . 41 3298.267 Alive . . 41 3198.667 Alive . . 41 3099.267 Alive . . 41 29100.233 Alive . . 41 28100.533 Alive . . 41 27103.100 Alive . . 41 26103.300 Alive . . 41 25105.167 Alive . . 41 24105.400 Alive . . 41 23106.233 Alive . . 41 22107.400 Alive . . 41 21107.800 Alive . . 41 20108.533 Alive . . 41 19108.900 Alive . . 41 18109.167 Alive . . 41 17109.167 Alive . . 41 16111.233 Alive . . 41 15111.533 Alive . . 41 14114.833 Alive . . 41 13117.233 Alive . . 41 12117.800 Alive . . 41 11119.267 Alive . . 41 10120.567 Alive . . 41 9122.000 Alive . . 41 8122.133 Alive . . 41 7122.233 Alive . . 41 6125.100 Alive . . 41 5126.000 Alive . . 41 4126.600 Alive . . 41 3128.567 Alive . . 41 2128.933 Alive . . 41 1129.033 Alive . . 41 03.000 Alive . . 0 4223.267 Alive . . 0 4213.567 Alive . . 0 4204.533 Alive . . 0 4194.533 Alive . . 0 4184.700 Alive . . 0 4174.700 Alive . . 0 4164.800 Alive . . 0 4155.400 Alive . . 0 4145.433 Alive . . 0 4135.967 Alive . . 0 4126.167 Alive . . 0 4116.400 Alive . . 0 4106.533 Alive . . 0 4096.567 Alive . . 0 4087.100 Ex .998 .002 1 4077.133 Alive . . 1 4067.200 Alive . . 1 4057.267 Alive . . 1 4047.433 Alive . . 1 4037.633 Alive . . 1 4027.700 Alive . . 1 4017.733 Alive . . 1 4007.833 Alive . . 1 3997.900 Alive . . 1 3987.900 Alive . . 1 3978.167 Alive . . 1 3968.267 Alive . . 1 3958.267 Alive . . 1 3948.500 Alive . . 1 3938.867 Alive . . 1 3929.100 Alive . . 1 3919.100 Alive . . 1 3909.100 Alive . . 1 3899.300 Alive . . 1 3889.367 Alive . . 1 3879.400 Alive . . 1 3869.467 Alive . . 1 3859.767 Alive . . 1 3849.800 Alive . . 1 3839.867 Alive . . 1 3829.900 Alive . . 1 38110.100 Alive . . 1 38010.167 Alive . . 1 37910.333 Alive . . 1 37810.600 Alive . . 1 37710.933 Alive . . 1 37611.133 Alive . . 1 37511.500 Alive . . 1 37411.633 Alive . . 1 37311.967 Alive . . 1 37212.000 Alive . . 1 37112.167 Alive . . 1 37012.167 Alive . . 1 36912.233 Alive . . 1 36812.267 Alive . . 1 36712.433 Alive . . 1 36612.567 Alive . . 1 36512.600 Alive . . 1 36412.833 Ex .995 .004 2 36312.967 Alive . . 2 36213.000 Alive . . 2 36113.033 Ex .992 .005 3 36013.100 Ex .989 .005 4 35913.333 Alive . . 4 35813.433 Alive . . 4 35713.767 Alive . . 4 35614.633 Alive . . 4 35514.667 Alive . . 4 35414.933 Alive . . 4 35315.167 Alive . . 4 35215.167 Alive . . 4 35115.233 Alive . . 4 35015.533 Alive . . 4 34915.733 Alive . . 4 34815.767 Alive . . 4 34715.800 Alive . . 4 34615.900 Alive . . 4 34516.000 Alive . . 4 34416.133 Alive . . 4 34316.167 Alive . . 4 34216.367 Ex .986 .006 5 34116.367 Alive . . 5 34016.433 Alive . . 5 33916.533 Alive . . 5 33816.967 Alive . . 5 33717.200 Alive . . 5 33617.300 Alive . . 5 33517.667 Ex .983 .007 6 33417.667 Alive . . 6 33317.867 Alive . . 6 33217.933 Alive . . 6 33118.033 Alive . . 6 33018.433 Alive . . 6 32918.667 Alive . . 6 32818.667 Alive . . 6 32718.667 Alive . . 6 32619.167 Alive . . 6 32519.633 Alive . . 6 32419.800 Alive . . 6 32320.300 Alive . . 6 32220.500 Alive . . 6 32120.500 Alive . . 6 32021.000 Alive . . 6 31921.067 Alive . . 6 31821.267 Alive . . 6 31721.600 Alive . . 6 31622.133 Alive . . 6 31522.200 Ex .980 .007 7 31422.533 Alive . . 7 31322.700 Alive . . 7 31222.900 Alive . . 7 31122.933 Alive . . 7 31023.133 Alive . . 7 30923.200 Alive . . 7 30823.367 Alive . . 7 30723.533 Alive . . 7 30623.533 Alive . . 7 30523.633 Alive . . 7 30423.900 Alive . . 7 30323.900 Alive . . 7 30224.000 Alive . . 7 30124.033 Alive . . 7 30024.067 Alive . . 7 29924.167 Alive . . 7 29824.300 Alive . . 7 29724.433 Alive . . 7 29624.533 Alive . . 7 29524.633 Alive . . 7 29424.767 Alive . . 7 29325.500 Alive . . 7 29225.533 Alive . . 7 29125.867 Alive . . 7 29025.933 Alive . . 7 28927.267 Alive . . 7 28827.300 Alive . . 7 28727.400 Alive . . 7 28627.400 Alive . . 7 28527.467 Alive . . 7 28427.500 Alive . . 7 28327.500 Alive . . 7 28227.533 Alive . . 7 28127.933 Alive . . 7 28028.033 Alive . . 7 27928.100 Alive . . 7 27828.600 Alive . . 7 27728.667 Alive . . 7 27628.700 Alive . . 7 27528.933 Alive . . 7 27429.167 Alive . . 7 27329.300 Alive . . 7 27229.433 Alive . . 7 27129.700 Alive . . 7 27029.767 Alive . . 7 26929.900 Alive . . 7 26829.900 Alive . . 7 26730.000 Alive . . 7 26630.633 Alive . . 7 26531.000 Alive . . 7 26431.533 Alive . . 7 26332.200 Alive . . 7 26232.467 Alive . . 7 26132.600 Alive . . 7 26033.467 Ex .977 .008 8 25933.567 Alive . . 8 25833.567 Alive . . 8 25733.800 Alive . . 8 25633.967 Alive . . 8 25534.033 Alive . . 8 25434.133 Alive . . 8 25334.267 Alive . . 8 25234.333 Alive . . 8 25134.767 Alive . . 8 25035.100 Alive . . 8 24935.233 Alive . . 8 24835.833 Alive . . 8 24736.400 Alive . . 8 24636.633 Ex .973 .009 9 24536.767 Alive . . 9 24436.833 Alive . . 9 24337.100 Alive . . 9 24237.300 Alive . . 9 24137.567 Alive . . 9 24037.600 Alive . . 9 23937.700 Alive . . 9 23837.800 Alive . . 9 23737.867 Alive . . 9 23637.967 Alive . . 9 23538.067 Alive . . 9 23438.900 Alive . . 9 23339.067 Alive . . 9 23239.200 Alive . . 9 23139.300 Alive . . 9 23039.367 Alive . . 9 22939.467 Alive . . 9 22839.700 Alive . . 9 22739.967 Alive . . 9 22640.133 Alive . . 9 22540.533 Alive . . 9 22440.600 Alive . . 9 22340.633 Alive . . 9 22240.767 Alive . . 9 22140.800 Ex .968 .010 10 22040.833 Alive . . 10 21941.067 Alive . . 10 21841.133 Alive . . 10 21741.200 Alive . . 10 21641.300 Alive . . 10 21541.567 Alive . . 10 21442.167 Alive . . 10 21342.333 Alive . . 10 21242.400 Alive . . 10 21142.433 Ex .964 .011 11 21043.100 Alive . . 11 20943.467 Alive . . 11 20843.667 Alive . . 11 20743.900 Alive . . 11 20644.100 Alive . . 11 20544.367 Ex .959 .012 12 20444.433 Alive . . 12 20344.900 Alive . . 12 20245.133 Ex .954 .013 13 20145.267 Alive . . 13 20045.633 Alive . . 13 19945.867 Alive . . 13 19846.100 Alive . . 13 19746.200 Alive . . 13 19646.267 Alive . . 13 19546.400 Alive . . 13 19446.667 Alive . . 13 19346.800 Alive . . 13 19246.833 Alive . . 13 19146.900 Alive . . 13 19046.933 Alive . . 13 18947.033 Alive . . 13 18847.033 Alive . . 13 18747.233 Alive . . 13 18647.233 Alive . . 13 18547.767 Alive . . 13 18447.867 Alive . . 13 18348.067 Alive . . 13 18248.400 Alive . . 13 18148.400 Alive . . 13 18048.400 Alive . . 13 17948.533 Ex .949 .014 14 17848.933 Alive . . 14 17749.533 Alive . . 14 17649.700 Alive . . 14 17549.833 Alive . . 14 17449.867 Alive . . 14 17350.767 Alive . . 14 17250.833 Alive . . 14 17150.900 Alive . . 14 17051.033 Alive . . 14 16951.267 Alive . . 14 16851.333 Alive . . 14 16751.367 Alive . . 14 16651.800 Alive . . 14 16551.800 Alive . . 14 16452.400 Alive . . 14 16352.467 Alive . . 14 16253.067 Alive . . 14 16153.200 Alive . . 14 16053.600 Alive . . 14 15954.267 Alive . . 14 15854.300 Alive . . 14 15754.300 Alive . . 14 15654.600 Alive . . 14 15554.633 Alive . . 14 15455.000 Alive . . 14 15355.033 Alive . . 14 15255.800 Alive . . 14 15155.867 Alive . . 14 15056.233 Ex .943 .015 15 14956.467 Alive . . 15 14856.567 Alive . . 15 14756.567 Alive . . 15 14656.833 Alive . . 15 14556.933 Alive . . 15 14457.033 Alive . . 15 14357.067 Alive . . 15 14257.233 Alive . . 15 14157.600 Alive . . 15 14057.700 Alive . . 15 13957.800 Alive . . 15 13857.833 Alive . . 15 13758.100 Alive . . 15 13658.367 Alive . . 15 13558.700 Alive . . 15 13458.800 Alive . . 15 13359.000 Alive . . 15 13259.100 Alive . . 15 13159.133 Ex .935 .017 16 13059.133 Alive . . 16 12959.233 Alive . . 16 12859.500 Alive . . 16 12759.733 Alive . . 16 12660.100 Alive . . 16 12560.167 Alive . . 16 12460.267 Alive . . 16 12361.167 Alive . . 16 12261.267 Alive . . 16 12161.367 Alive . . 16 12061.567 Alive . . 16 11962.067 Alive . . 16 11862.233 Alive . . 16 11762.267 Alive . . 16 11663.000 Alive . . 16 11563.433 Alive . . 16 11463.633 Alive . . 16 11363.633 Alive . . 16 11263.667 Alive . . 16 11163.800 Alive . . 16 11064.100 Alive . . 16 10964.367 Alive . . 16 10864.500 Alive . . 16 10764.500 Alive . . 16 10664.933 Alive . . 16 10565.233 Alive . . 16 10465.400 Alive . . 16 10365.833 Alive . . 16 10266.000 Ex .926 .019 17 10166.500 Alive . . 17 10067.633 Alive . . 17 9967.633 Alive . . 17 9867.767 Alive . . 17 9767.933 Alive . . 17 9668.067 Alive . . 17 9568.100 Alive . . 17 9468.200 Alive . . 17 9369.033 Alive . . 17 9269.800 Alive . . 17 9169.967 Alive . . 17 9070.300 Alive . . 17 8971.000 Alive . . 17 8871.133 Alive . . 17 8771.467 Alive . . 17 8671.633 Alive . . 17 8571.933 Alive . . 17 8473.000 Alive . . 17 8373.033 Ex .915 .022 18 8273.033 Alive . . 18 8173.200 Alive . . 18 8073.400 Alive . . 18 7973.633 Alive . . 18 7874.167 Alive . . 18 7774.200 Alive . . 18 7674.433 Alive . . 18 7574.900 Alive . . 18 7475.600 Alive . . 18 7375.633 Ex .902 .025 19 7276.000 Alive . . 19 7176.333 Alive . . 19 7076.500 Alive . . 19 6976.633 Ex .889 .028 20 6877.200 Alive . . 20 6779.400 Alive . . 20 6680.000 Alive . . 20 6580.000 Alive . . 20 6480.400 Alive . . 20 6380.467 Ex .875 .031 21 6280.467 Alive . . 21 6180.500 Alive . . 21 6080.533 Alive . . 21 5980.700 Alive . . 21 5880.900 Alive . . 21 5781.200 Alive . . 21 5681.367 Alive . . 21 5582.333 Alive . . 21 5483.067 Alive . . 21 5383.067 Alive . . 21 5283.300 Alive . . 21 5183.633 Alive . . 21 5084.433 Alive . . 21 4986.033 Alive . . 21 4886.567 Alive . . 21 4787.800 Alive . . 21 4689.133 Alive . . 21 4589.300 Alive . . 21 4489.833 Alive . . 21 4390.100 Alive . . 21 4290.400 Alive . . 21 4190.967 Alive . . 21 4091.267 Alive . . 21 3992.100 Alive . . 21 3892.400 Alive . . 21 3792.467 Alive . . 21 3693.333 Alive . . 21 3593.900 Alive . . 21 3494.500 Alive . . 21 3394.967 Alive . . 21 3295.333 Alive . . 21 3196.133 Alive . . 21 3096.500 Ex .846 .041 22 2996.833 Alive . . 22 2896.833 Alive . . 22 2799.300 Alive . . 22 2699.433 Alive . . 22 2599.600 Alive . . 22 24101.867 Alive . . 22 23102.900 Alive . . 22 22103.567 Alive . . 22 21104.233 Alive . . 22 20104.467 Alive . . 22 19105.467 Alive . . 22 18106.200 Alive . . 22 17108.933 Alive . . 22 16109.867 Alive . . 22 15109.900 Alive . . 22 14110.100 Alive . . 22 13114.067 Alive . . 22 12117.733 Alive . . 22 11118.833 Alive . . 22 10119.367 Alive . . 22 9120.067 Alive . . 22 8120.167 Alive . . 22 7125.367 Alive . . 22 6125.400 Alive . . 22 5127.867 Alive . . 22 4130.233 Alive . . 22 3132.233 Alive . . 22 2132.667 Alive . . 22 1133.800 Alive . . 22 02.633 Ex .997 .003 1 3673.000 Alive . . 1 3663.533 Alive . . 1 3653.567 Alive . . 1 3643.967 Alive . . 1 3634.133 Alive . . 1 3624.133 Alive . . 1 3614.267 Alive . . 1 3604.567 Alive . . 1 3594.867 Alive . . 1 3584.900 Alive . . 1 3575.267 Alive . . 1 3565.300 Alive . . 1 3556.100 Alive . . 1 3546.700 Alive . . 1 3536.900 Alive . . 1 3527.033 Alive . . 1 3517.400 Alive . . 1 3507.700 Alive . . 1 3497.733 Alive . . 1 3487.767 Alive . . 1 3477.833 Alive . . 1 3467.900 Alive . . 1 3458.600 Alive . . 1 3448.600 Alive . . 1 3439.300 Ex .994 .004 2 3429.467 Alive . . 2 3419.467 Alive . . 2 3409.500 Alive . . 2 3399.533 Alive . . 2 3389.733 Alive . . 2 3379.833 Alive . . 2 3369.900 Alive . . 2 33510.500 Alive . . 2 33410.700 Alive . . 2 33311.067 Alive . . 2 33211.167 Alive . . 2 33111.300 Alive . . 2 33011.433 Alive . . 2 32911.967 Alive . . 2 32812.000 Ex .991 .005 3 32712.300 Alive . . 3 32612.367 Alive . . 3 32512.567 Alive . . 3 32412.633 Alive . . 3 32312.767 Alive . . 3 32212.767 Alive . . 3 32112.800 Alive . . 3 32013.067 Alive . . 3 31913.233 Alive . . 3 31813.467 Alive . . 3 31713.600 Alive . . 3 31613.667 Alive . . 3 31513.900 Alive . . 3 31414.033 Alive . . 3 31314.300 Alive . . 3 31214.433 Alive . . 3 31114.500 Alive . . 3 31014.733 Ex .988 .006 4 30914.800 Alive . . 4 30814.800 Alive . . 4 30715.333 Alive . . 4 30615.600 Alive . . 4 30515.833 Alive . . 4 30416.067 Alive . . 4 30316.200 Ex .985 .007 5 30216.200 Alive . . 5 30116.333 Alive . . 5 30016.500 Alive . . 5 29916.633 Alive . . 5 29816.667 Alive . . 5 29717.033 Alive . . 5 29617.233 Alive . . 5 29517.233 Alive . . 5 29417.300 Alive . . 5 29317.333 Alive . . 5 29217.400 Alive . . 5 29117.633 Alive . . 5 29017.733 Alive . . 5 28917.800 Alive . . 5 28818.167 Alive . . 5 28718.667 Alive . . 5 28618.800 Alive . . 5 28518.867 Alive . . 5 28418.933 Alive . . 5 28319.333 Alive . . 5 28219.700 Alive . . 5 28119.800 Alive . . 5 28020.033 Alive . . 5 27920.100 Alive . . 5 27820.200 Alive . . 5 27720.733 Alive . . 5 27621.000 Alive . . 5 27521.267 Ex .981 .008 6 27421.600 Alive . . 6 27321.800 Alive . . 6 27222.067 Alive . . 6 27122.300 Alive . . 6 27022.333 Alive . . 6 26922.567 Alive . . 6 26822.667 Alive . . 6 26722.867 Alive . . 6 26622.967 Alive . . 6 26523.000 Alive . . 6 26423.367 Alive . . 6 26323.400 Alive . . 6 26223.400 Alive . . 6 26123.667 Alive . . 6 26024.700 Alive . . 6 25925.033 Alive . . 6 25825.167 Alive . . 6 25725.367 Alive . . 6 25625.433 Alive . . 6 25525.633 Alive . . 6 25425.800 Alive . . 6 25325.833 Alive . . 6 25225.967 Alive . . 6 25126.000 Alive . . 6 25026.000 Alive . . 6 24926.167 Alive . . 6 24826.367 Alive . . 6 24726.600 Ex .977 .009 7 24626.733 Alive . . 7 24526.833 Alive . . 7 24427.133 Alive . . 7 24327.400 Ex .973 .009 8 24227.400 Alive . . 8 24127.500 Alive . . 8 24027.767 Alive . . 8 23928.133 Alive . . 8 23828.667 Alive . . 8 23728.933 Alive . . 8 23629.267 Ex .969 .010 9 23529.300 Alive . . 9 23429.400 Alive . . 9 23329.900 Alive . . 9 23230.000 Alive . . 9 23130.067 Alive . . 9 23030.100 Alive . . 9 22930.233 Ex .965 .011 10 22830.533 Alive . . 10 22730.567 Alive . . 10 22631.067 Alive . . 10 22531.233 Alive . . 10 22431.233 Alive . . 10 22331.500 Alive . . 10 22231.700 Alive . . 10 22132.167 Alive . . 10 22032.200 Alive . . 10 21932.600 Alive . . 10 21832.967 Alive . . 10 21733.033 Alive . . 10 21633.433 Alive . . 10 21533.567 Alive . . 10 21434.267 Alive . . 10 21335.100 Alive . . 10 21235.133 Alive . . 10 21135.233 Alive . . 10 21035.767 Alive . . 10 20935.867 Alive . . 10 20835.900 Alive . . 10 20735.900 Alive . . 10 20636.000 Alive . . 10 20536.300 Alive . . 10 20436.400 Alive . . 10 20336.433 Alive . . 10 20236.933 Alive . . 10 20137.267 Alive . . 10 20037.367 Alive . . 10 19937.433 Alive . . 10 19837.500 Alive . . 10 19737.700 Alive . . 10 19638.200 Alive . . 10 19538.667 Alive . . 10 19438.767 Alive . . 10 19338.767 Alive . . 10 19238.800 Alive . . 10 19138.967 Alive . . 10 19039.400 Alive . . 10 18939.400 Alive . . 10 18839.467 Alive . . 10 18739.500 Ex .960 .012 11 18640.100 Alive . . 11 18540.167 Ex .955 .013 12 18440.267 Alive . . 12 18340.533 Alive . . 12 18240.600 Alive . . 12 18140.733 Alive . . 12 18040.733 Alive . . 12 17940.800 Alive . . 12 17841.033 Alive . . 12 17741.200 Alive . . 12 17641.467 Ex .949 .014 13 17541.800 Alive . . 13 17442.167 Alive . . 13 17342.167 Alive . . 13 17242.367 Alive . . 13 17142.400 Alive . . 13 17042.433 Ex .944 .015 14 16942.533 Alive . . 14 16843.400 Alive . . 14 16743.467 Alive . . 14 16643.600 Alive . . 14 16543.700 Alive . . 14 16443.867 Alive . . 14 16344.067 Alive . . 14 16244.767 Alive . . 14 16144.967 Alive . . 14 16045.467 Alive . . 14 15945.667 Alive . . 14 15845.700 Alive . . 14 15745.933 Alive . . 14 15646.433 Alive . . 14 15546.633 Alive . . 14 15446.967 Alive . . 14 15347.067 Alive . . 14 15247.133 Alive . . 14 15147.433 Alive . . 14 15047.967 Ex .937 .016 15 14948.400 Alive . . 15 14848.467 Alive . . 15 14748.767 Alive . . 15 14649.233 Alive . . 15 14549.367 Alive . . 15 14449.367 Alive . . 15 14349.467 Alive . . 15 14249.600 Alive . . 15 14149.667 Alive . . 15 14050.333 Alive . . 15 13950.667 Ex .931 .017 16 13850.800 Alive . . 16 13751.100 Alive . . 16 13651.467 Alive . . 16 13551.500 Alive . . 16 13451.700 Alive . . 16 13351.700 Alive . . 16 13251.833 Alive . . 16 13151.967 Alive . . 16 13052.033 Alive . . 16 12952.033 Alive . . 16 12852.133 Alive . . 16 12752.433 Alive . . 16 12652.467 Alive . . 16 12552.700 Ex .923 .019 17 12452.933 Alive . . 17 12353.000 Alive . . 17 12253.167 Alive . . 17 12153.300 Alive . . 17 12053.333 Alive . . 17 11953.367 Alive . . 17 11853.367 Alive . . 17 11753.633 Alive . . 17 11653.867 Alive . . 17 11554.433 Alive . . 17 11455.033 Alive . . 17 11355.633 Alive . . 17 11255.767 Alive . . 17 11155.867 Alive . . 17 11056.033 Alive . . 17 10957.433 Alive . . 17 10857.867 Alive . . 17 10757.900 Alive . . 17 10658.033 Alive . . 17 10558.367 Alive . . 17 10458.433 Alive . . 17 10358.733 Alive . . 17 10258.867 Alive . . 17 10159.400 Alive . . 17 10059.500 Alive . . 17 9959.700 Alive . . 17 9859.733 Alive . . 17 9759.767 Alive . . 17 9660.067 Alive . . 17 9561.100 Alive . . 17 9461.167 Alive . . 17 9361.900 Alive . . 17 9261.967 Alive . . 17 9162.233 Alive . . 17 9062.467 Alive . . 17 8962.500 Alive . . 17 8863.033 Alive . . 17 8763.067 Alive . . 17 8663.267 Alive . . 17 8563.267 Alive . . 17 8463.467 Alive . . 17 8364.000 Alive . . 17 8264.300 Alive . . 17 8165.067 Alive . . 17 8065.333 Alive . . 17 7965.500 Alive . . 17 7865.667 Alive . . 17 7766.233 Alive . . 17 7666.300 Alive . . 17 7566.600 Alive . . 17 7466.800 Ex .911 .022 18 7367.633 Alive . . 18 7267.900 Alive . . 18 7168.167 Alive . . 18 7068.900 Alive . . 18 6969.033 Alive . . 18 6869.800 Alive . . 18 6770.633 Alive . . 18 6670.733 Alive . . 18 6570.800 Alive . . 18 6470.900 Alive . . 18 6370.967 Alive . . 18 6271.133 Alive . . 18 6171.533 Alive . . 18 6072.433 Alive . . 18 5973.733 Alive . . 18 5873.833 Alive . . 18 5774.100 Alive . . 18 5674.433 Alive . . 18 5574.533 Alive . . 18 5475.700 Alive . . 18 5375.733 Alive . . 18 5276.300 Alive . . 18 5177.200 Alive . . 18 5077.233 Alive . . 18 4977.733 Alive . . 18 4879.033 Alive . . 18 4779.800 Alive . . 18 4679.800 Alive . . 18 4579.867 Alive . . 18 4480.100 Alive . . 18 4380.800 Alive . . 18 4281.900 Alive . . 18 4181.933 Ex .888 .031 19 4082.600 Ex .866 .037 20 3982.933 Alive . . 20 3882.967 Alive . . 20 3783.067 Alive . . 20 3683.767 Alive . . 20 3584.433 Alive . . 20 3484.467 Alive . . 20 3384.733 Alive . . 20 3285.733 Alive . . 20 3186.200 Alive . . 20 3088.933 Alive . . 20 2989.033 Alive . . 20 2889.833 Alive . . 20 2791.667 Alive . . 20 2691.967 Alive . . 20 2592.233 Alive . . 20 2492.533 Alive . . 20 2394.767 Alive . . 20 2295.200 Alive . . 20 2195.633 Alive . . 20 2097.033 Alive . . 20 1997.767 Alive . . 20 1898.500 Alive . . 20 17100.100 Alive . . 20 16100.733 Alive . . 20 15101.667 Alive . . 20 14103.433 Alive . . 20 13105.733 Alive . . 20 12106.300 Alive . . 20 11107.367 Alive . . 20 10110.067 Alive . . 20 9112.433 Alive . . 20 8112.867 Alive . . 20 7113.267 Alive . . 20 6114.067 Alive . . 20 5117.267 Alive . . 20 4119.867 Alive . . 20 3122.600 Alive . . 20 2129.567 Alive . . 20 1129.733 Alive . . 20 0123456789101112131415161718192021222324252627282930313233343536373839404142434445464748495051525354555657585960616263646566676869707172737475767778798081828384858687888990919293949596979899100101102103104105106107108109110111112113114115116117118119120121122123124125126127128129130131132133134135136137138139140141142143144145146147148149150151152153154155156157158159160161162163164165166167168169170171172173174175176177178179180181182183184185186187188189190191192193194195196197198199200201202203204205206207208209210211212213214215216217218219220221222223224225226227228229230231232233234235236237238239240241242243244245246247248249250251252253254255256257258259260261262263264265266267268269270271272273274275276277278279280281282283284285286287288289290291292293294295296297298299300301302303304305306307308309310311312313314315316317318319320321322323324325326327328329330331332333334335336337338339340341342343344345346347348349350351352353354355356357358359360361362363364365366367368369370371372373374375376377378379380381382383384385386387388389390391392393394395396397398399400401402403404405406407408409410411412413414415416123456789101112131415161718192021222324252627282930313233343536373839404142434445464748495051525354555657585960616263646566676869707172737475767778798081828384858687888990919293949596979899100101102103104105106107108109110111112113114115116117118119120121122123124125126127128129130131132133134135136137138139140141142143144145146147148149150151152153154155156157158159160161162163164165166167168169170171172173174175176177178179180181182183184185186187188189190191192193194195196197198199200201202203204205206207208209210211212213214215216217218219220221222223224225226227228229230231232233234235236237238239240241242243244245246247248249250251252253254255256257258259260261262263264265266267268269270271272273274275276277278279280281282283284285286287288289290291292293294295296297298299300301302303304305306307308309310311312313314315316317318319320321322323324325326327328329330331332333334335336337338339340341342343344345346347348349350351352353354355356357358359360361362363364365366367368369370371372373374375376377378379380381382383384385386387388389390391392393394395396397398399400401402403404405406407408409410411412413414415416417418419420421422423123456789101112131415161718192021222324252627282930313233343536373839404142434445464748495051525354555657585960616263646566676869707172737475767778798081828384858687888990919293949596979899100101102103104105106107108109110111112113114115116117118119120121122123124125126127128129130131132133134135136137138139140141142143144145146147148149150151152153154155156157158159160161162163164165166167168169170171172173174175176177178179180181182183184185186187188189190191192193194195196197198199200201202203204205206207208209210211212213214215216217218219220221222223224225226227228229230231232233234235236237238239240241242243244245246247248249250251252253254255256257258259260261262263264265266267268269270271272273274275276277278279280281282283284285286287288289290291292293294295296297298299300301302303304305306307308309310311312313314315316317318319320321322323324325326327328329330331332333334335336337338339340341342343344345346347348349350351352353354355356357358359360361362363364365366367368agegr<4950-6465+Time Status Estimate Std. ErrorCumulativeProportion Survivingat the Time N of CumulativeEvents N of Remaining CasesSurvival Table3.367 Alive . . 0 4153.567 Alive . . 0 4143.567 Alive . . 0 4133.833 Alive . . 0 4124.167 Alive . . 0 4114.367 Alive . . 0 4104.733 Alive . . 0 4094.867 Alive . . 0 4085.800 Alive . . 0 4075.933 Alive . . 0 4066.067 Alive . . 0 4056.367 Alive . . 0 4046.567 Alive . . 0 4036.867 Alive . . 0 4027.067 Alive . . 0 4017.167 Alive . . 0 4007.300 Alive . . 0 3997.300 Alive . . 0 3987.367 Alive . . 0 3978.167 Alive . . 0 3968.167 Alive . . 0 3958.233 Alive . . 0 3948.667 Alive . . 0 3938.867 Alive . . 0 3929.233 Alive . . 0 3919.300 Alive . . 0 3909.800 Alive . . 0 3899.900 Alive . . 0 38810.233 Alive . . 0 38710.567 Alive . . 0 38610.600 Alive . . 0 38510.633 Alive . . 0 38410.933 Alive . . 0 38310.933 Alive . . 0 38211.000 Alive . . 0 38111.000 Alive . . 0 38011.033 Ex .997 .003 1 37911.200 Alive . . 1 37811.667 Alive . . 1 37711.733 Alive . . 1 37612.000 Alive . . 1 37512.200 Ex .995 .004 2 37412.433 Ex .992 .005 3 37312.567 Alive . . 3 37213.067 Alive . . 3 37113.067 Alive . . 3 37013.367 Alive . . 3 36913.600 Alive . . 3 36813.767 Alive . . 3 36713.933 Alive . . 3 36614.133 Alive . . 3 36514.400 Alive . . 3 36414.733 Alive . . 3 36315.133 Alive . . 3 36215.600 Alive . . 3 36115.667 Alive . . 3 36016.100 Alive . . 3 35916.567 Alive . . 3 35816.700 Alive . . 3 35717.133 Ex .989 .005 4 35617.133 Alive . . 4 35517.200 Alive . . 4 35417.533 Alive . . 4 35317.767 Alive . . 4 35217.800 Alive . . 4 35118.100 Ex .986 .006 5 35018.300 Alive . . 5 34918.500 Alive . . 5 34818.500 Alive . . 5 34718.667 Alive . . 5 34618.667 Alive . . 5 34518.700 Alive . . 5 34418.767 Ex .984 .007 6 34318.867 Alive . . 6 34219.133 Alive . . 6 34119.467 Alive . . 6 34019.767 Alive . . 6 33919.833 Ex .981 .007 7 33819.867 Alive . . 7 33720.267 Alive . . 7 33620.467 Alive . . 7 33520.567 Alive . . 7 33420.733 Alive . . 7 33320.867 Alive . . 7 33221.000 Alive . . 7 33121.233 Alive . . 7 33021.767 Ex .978 .008 8 32921.967 Alive . . 8 32822.233 Alive . . 8 32722.367 Alive . . 8 32622.500 Alive . . 8 32522.500 Alive . . 8 32422.533 Alive . . 8 32322.733 Alive . . 8 32222.867 Alive . . 8 32122.900 Alive . . 8 32022.933 Alive . . 8 31923.400 Alive . . 8 31823.567 Ex .975 .008 9 31723.767 Alive . . 9 31624.000 Alive . . 9 31524.200 Alive . . 9 31424.333 Ex .972 .009 10 31324.333 Alive . . 10 31224.633 Ex .968 .009 11 31124.700 Alive . . 11 31025.233 Ex .965 .010 12 30925.367 Ex .962 .010 13 30825.400 Alive . . 13 30725.433 Ex .959 .011 14 30625.700 Alive . . 14 30525.833 Alive . . 14 30425.933 Alive . . 14 30326.133 Ex .956 .011 15 30226.167 Alive . . 15 30126.300 Alive . . 15 30026.633 Alive . . 15 29926.933 Alive . . 15 29827.400 Alive . . 15 29727.633 Ex .953 .012 16 29627.733 Alive . . 16 29528.067 Alive . . 16 29428.133 Alive . . 16 29328.333 Ex .949 .012 17 29229.533 Ex .946 .012 18 29129.567 Ex .943 .013 19 29030.400 Alive . . 19 28930.933 Alive . . 19 28831.167 Alive . . 19 28731.200 Alive . . 19 28631.367 Alive . . 19 28531.533 Ex .940 .013 20 28431.567 Alive . . 20 28331.733 Alive . . 20 28232.100 Alive . . 20 28132.367 Alive . . 20 28032.667 Alive . . 20 27932.967 Alive . . 20 27833.700 Alive . . 20 27733.833 Alive . . 20 27634.067 Alive . . 20 27534.400 Alive . . 20 27434.600 Alive . . 20 27334.767 Alive . . 20 27234.833 Alive . . 20 27134.900 Alive . . 20 27035.233 Alive . . 20 26935.367 Alive . . 20 26835.400 Alive . . 20 26735.667 Alive . . 20 26635.700 Alive . . 20 26535.733 Alive . . 20 26436.200 Alive . . 20 26336.333 Alive . . 20 26236.367 Alive . . 20 26136.500 Alive . . 20 26036.600 Alive . . 20 25936.867 Ex .936 .014 21 25836.933 Alive . . 21 25736.967 Alive . . 21 25637.067 Alive . . 21 25537.067 Alive . . 21 25437.133 Alive . . 21 25337.467 Alive . . 21 25237.700 Ex .932 .014 22 25138.033 Alive . . 22 25038.333 Alive . . 22 24938.400 Alive . . 22 24838.867 Alive . . 22 24738.967 Alive . . 22 24639.500 Alive . . 22 24539.833 Alive . . 22 24440.100 Ex .928 .014 23 24340.300 Alive . . 23 24240.567 Alive . . 23 24140.700 Alive . . 23 24041.167 Alive . . 23 23941.267 Ex .925 .015 24 23841.367 Alive . . 24 23741.400 Ex .921 .015 25 23641.433 Alive . . 25 23541.533 Ex .917 .016 26 23441.733 Alive . . 26 23341.800 Alive . . 26 23241.900 Alive . . 26 23142.233 Ex .913 .016 27 23042.300 Alive . . 27 22942.333 Alive . . 27 22842.867 Alive . . 27 22742.933 Alive . . 27 22642.967 Ex .909 .017 28 22543.400 Alive . . 28 22443.500 Ex .905 .017 29 22343.567 Alive . . 29 22243.600 Alive . . 29 22143.633 Alive . . 29 22043.700 Alive . . 29 21943.867 Alive . . 29 21843.867 Alive . . 29 21744.367 Alive . . 29 21644.767 Alive . . 29 21545.200 Alive . . 29 21445.300 Ex .900 .017 30 21345.567 Alive . . 30 21245.933 Alive . . 30 21146.367 Alive . . 30 21046.467 Ex .896 .018 31 20946.600 Alive . . 31 20846.600 Alive . . 31 20746.833 Alive . . 31 20647.000 Alive . . 31 20547.067 Alive . . 31 20447.267 Alive . . 31 20347.733 Alive . . 31 20247.833 Alive . . 31 20147.833 Alive . . 31 20047.867 Alive . . 31 19948.100 Alive . . 31 19848.167 Alive . . 31 19748.533 Alive . . 31 19648.533 Alive . . 31 19548.667 Alive . . 31 19448.833 Alive . . 31 19348.933 Alive . . 31 19249.367 Alive . . 31 19149.533 Alive . . 31 19050.067 Alive . . 31 18950.133 Alive . . 31 18850.367 Alive . . 31 18750.567 Alive . . 31 18650.733 Alive . . 31 18550.833 Alive . . 31 18450.867 Alive . . 31 18350.900 Alive . . 31 18251.467 Alive . . 31 18152.233 Alive . . 31 18052.433 Alive . . 31 17952.933 Alive . . 31 17853.000 Alive . . 31 17753.133 Alive . . 31 17653.500 Ex .891 .019 32 17553.667 Alive . . 32 17453.667 Alive . . 32 17353.667 Alive . . 32 17253.700 Alive . . 32 17154.267 Alive . . 32 17054.333 Alive . . 32 16954.567 Alive . . 32 16854.600 Ex .886 .019 33 16754.833 Alive . . 33 16654.833 Alive . . 33 16554.900 Alive . . 33 16455.333 Alive . . 33 16355.433 Alive . . 33 16256.433 Alive . . 33 16156.467 Alive . . 33 16056.567 Ex .880 .020 34 15956.767 Alive . . 34 15857.033 Alive . . 34 15757.300 Alive . . 34 15657.400 Alive . . 34 15557.467 Alive . . 34 15458.067 Alive . . 34 15358.200 Alive . . 34 15258.367 Alive . . 34 15159.033 Ex .874 .021 35 15059.267 Alive . . 35 14959.500 Alive . . 35 14860.067 Alive . . 35 14760.200 Alive . . 35 14660.333 Alive . . 35 14560.500 Alive . . 35 14460.767 live . . 35 14360.867 Alive . . 35 14261.133 Alive . . 35 14161.133 Alive . . 35 14061.200 Alive . . 35 13961.267 Alive . . 35 13861.367 Alive . . 35 13762.033 Alive . . 35 13662.167 Alive . . 35 13562.267 live . . 35 13462.533 Ex .868 .021 36 13362.533 Alive . . 36 13262.733 Alive . . 36 13162.800 Alive . . 36 13062.833 Alive . . 36 12963.300 live . . 36 12863.633 Alive . . 36 12763.700 Alive . . 36 12663.800 Alive . . 36 12563.900 Alive . . 36 12464.167 Alive . . 36 12364.267 Ex .861 .022 37 12265.133 Alive . . 37 12166.533 live . . 37 12066.700 live . . 37 11966.767 live . . 37 11866.800 Ex .854 .023 38 11766.967 Alive . . 38 11666.967 Alive . . 38 11567.767 Alive . . 38 11467.767 live . . 38 11368.167 live . . 38 11268.367 Alive . . 38 11168.567 live . . 38 11068.833 live . . 38 10969.100 live . . 38 10869.333 live . . 38 10769.467 live . . 38 10669.500 live . . 38 10570.167 Alive . . 38 10471.200 live . . 38 10371.367 live . . 38 10271.700 live . . 38 10171.767 Alive . . 38 10072.633 Alive . . 38 9973.033 live . . 38 9873.033 live . . 38 9773.467 live . . 38 9673.533 live . . 38 9574.633 live . . 38 9474.733 live . . 38 9374.967 live . . 38 9275.667 live . . 38 9176.133 Ex .844 .025 39 9076.200 live . . 39 8976.233 live . . 39 8876.500 live . . 39 8776.900 live . . 39 8677.900 live . . 39 8578.200 live . . 39 8478.667 live . . 39 8378.867 live . . 39 8278.867 live . . 39 8178.933 live . . 39 8079.333 live . . 39 7979.567 live . . 39 7880.000 live . . 39 7780.300 live . . 39 7680.400 live . . 39 7581.133 live . . 39 7481.167 live . . 39 7381.233 Alive . . 39 7281.367 live . . 39 7181.467 live . . 39 7081.767 live . . 39 6981.833 live . . 39 6882.667 live . . 39 6782.667 live . . 39 6682.667 live . . 39 6583.033 live . . 39 6483.267 Ex .831 .028 40 6383.533 live . . 40 6283.867 live . . 40 6184.200 live . . 40 6084.633 live . . 40 5984.667 live . . 40 5884.800 live . . 40 5784.933 live . . 40 5685.167 live . . 40 5585.567 live . . 40 5486.200 live . . 40 5387.000 live . . 40 5287.067 live . . 40 5187.133 live . . 40 5087.500 live . . 40 4987.900 live . . 40 4888.733 live . . 40 4789.133 live . . 40 4689.400 Alive . . 40 4589.967 live . . 40 4490.167 live . . 40 4390.333 live . . 40 4290.933 live . . 40 4191.167 live . . 40 4091.933 live . . 40 3993.300 live . . 40 3894.167 live . . 40 3794.333 Ex .808 .035 41 3696.400 live . . 41 3596.400 live . . 41 3497.100 live . . 41 3397.400 live . . 41 3298.267 live . . 41 3198.667 live . . 41 3099.267 live . . 41 29100.233 live . . 41 28100.533 live . . 41 27103.100 live . . 41 26103.300 live . . 41 25105.167 live . . 41 24105.400 live . . 41 23106.233 live . . 41 22107.400 live . . 41 21107.800 live . . 41 20108.533 live . . 41 19108.900 Alive . . 41 18109.167 live . . 41 17109.167 live . . 41 16111.233 live . . 41 15111.533 live . . 41 14114.833 live . . 41 13117.233 live . . 41 12117.800 live . . 41 11119.267 live . . 41 10120.567 live . . 41 9122.000 live . . 41 8122.133 live . . 41 7122.233 live . . 41 6125.100 live . . 41 5126.000 live . . 41 4126.600 live . . 41 3128.567 live . . 41 2128.933 live . . 41 1129.033 live . . 41 03.000 live . . 0 4223.267 live . . 0 4213.567 live . . 0 4204.533 live . . 0 4194.533 live . . 0 4184.700 live . . 0 4174.700 live . . 0 4164.800 live . . 0 4155.400 live . . 0 4145.433 live . . 0 4135.967 live . . 0 4126.167 live . . 0 4116.400 live . . 0 4106.533 live . . 0 4096.567 live . . 0 4087.100 Ex .998 .002 1 4077.133 live . . 1 4067.200 live . . 1 4057.267 live . . 1 4047.433 live . . 1 4037.633 live . . 1 4027.700 live . . 1 4017.733 live . . 1 4007.833 live . . 1 3997.900 live . . 1 3987.900 live . . 1 3978.167 live . . 1 3968.267 live . . 1 3958.267 live . . 1 3948.500 live . . 1 3938.867 live . . 1 3929.100 live . . 1 3919.100 live . . 1 3909.100 Alive . . 1 3899.300 live . . 1 3889.367 live . . 1 3879.400 live . . 1 3869.467 live . . 1 3859.767 live . . 1 3849.800 live . . 1 3839.867 live . . 1 3829.900 live . . 1 38110.100 live . . 1 38010.167 live . . 1 37910.333 live . . 1 37810.600 live . . 1 37710.933 live . . 1 37611.133 live . . 1 37511.500 live . . 1 37411.633 live . . 1 37311.967 live . . 1 37212.000 live . . 1 37112.167 live . . 1 37012.167 live . . 1 36912.233 live . . 1 36812.267 live . . 1 36712.433 live . . 1 36612.567 live . . 1 36512.600 live . . 1 36412.833 Ex .995 .004 2 36312.967 live . . 2 36213.000 live . . 2 36113.033 Ex .992 .005 3 36013.100 Ex .989 .005 4 35913.333 live . . 4 35813.433 live . . 4 35713.767 live . . 4 35614.633 live . . 4 35514.667 live . . 4 35414.933 live . . 4 35315.167 live . . 4 35215.167 live . . 4 3515. liv . . 4 505.533 liv . . 4 4915.733 live . . 4 34815.767 live . . 4 34715.800 live . . 4 34615.900 Alive . . 4 34516.000 live . . 4 34416.133 live . . 4 34316.167 Alive . . 4 34216.367 x .986 .006 5 34116.367 live . . 5 34016.433 live . . 5 3396.533 liv . . 5 3816.967 live . . 5 3377.200 liv . . 5 3617.300 live . . 5 3357.6 Ex .983 .007 6 347.6 liv . . 6 3317.867 live . . 6 33217.933 live . . 6 33118.033 live . . 6 33018.433 live . . 6 32918.667 live . . 6 32818.667 live . . 6 3278.667 liv . . 6 269. 67 liv . . 6 259.633 liv . . 6 2419.800 Alive . . 6 32320. 00 liv . . 6 2220.500 liv . . 6 2120.500 live . . 6 32021.000 live . . 6 31921.067 live . . 6 31821.267 live . . 6 31721.600 Alive . . 6 31622.133 live . . 6 31522.200 Ex .980 .007 7 1422.5 liv . . 7 1322.700 liv . . 7 1222.900 liv . . 7 1122.933 liv . . 7 1023.133 liv . . 7 0923.200 live . . 7 30823.367 live . . 7 30723.533 live . . 7 30623.533 live . . 7 30523.633 live . . 7 30423.900 live . . 7 3033.9 liv . . 7 024. liv . . 7 014. 33 liv . . 7 004.0 liv . . 7 2994.167 liv . . 7 2984.300 liv . . 7 29724.433 Alive . . 7 29624.533 live . . 7 29524.633 live . . 7 29424.767 live . . 7 29325.500 live . . 7 29225.533 live . . 7 2915.867 liv . . 2905.933 liv . . 2897.267 liv . . 2887.300 liv . . 2877.400 liv . . 2867.4 liv . . 28527.467 live . . 7 28427.500 live . . 7 28327.500 live . . 7 28227.533 live . . 7 28127.933 live . . 7 28028.033 live . . 7 2798.100 liv . . 788.600 liv . . 778. 67 liv . . 768. 00 liv . . 758.933 liv . . 749.167 liv . . 7329.300 live . . 7 27229.433 live . . 7 27129.700 live . . 7 27029.767 live . . 7 26929.900 live . . 7 26829.900 live . . 7 26730.000 liv . . 6630.633 liv . . 6531.0 liv . . 6431. liv . . 6332.200 liv . . 6232.467 liv . . 6132.600 live . . 7 26033.467 Ex .977 .008 8 25933.567 live . . 8 25833.567 live . . 8 25733.800 live . . 8 25633.967 live . . 8 25534.033 liv . . 8 5434.1 liv . . 8 5334.267 liv . . 8 5234.333 liv . . 8 5134.767 liv . . 8 5035.1 liv . . 8 495.233 liv . . 8 485.8 liv . . 8 4736.400 live . . 8 24636.633 Ex .973 .009 9 24536.767 live . . 9 24436.833 live . . 9 2437.1 liv . . 9 427.300 Alive . . 9 417. liv . . 9 407.600 liv . . 9 397.7 liv . . 9 387.800 liv . . 9 377.867 liv . . 9 367.967 liv . . 9 358.0 liv . . 9 348.900 liv . . 9 339.0 liv . . 9 3239.200 live . . 9 2319.300 liv . . 9 309.367 liv . . 9 299. 67 liv . . 9 289.700 Alive . . 279.9 liv . . 2640.1 liv . . 2540.533 liv . . 2440.6 liv . . 2340.633 liv . . 2240.767 live . . 9 22140.8 Ex .968 .010 10 2040. 33 liv . . 10 1941.0 liv . . 10 1841.133 liv . . 10 1741.200 liv . . 10 1641.3 liv . . 10 1541.5 liv . . 10 1442.167 liv . . 10 1342. 33 liv . . 10 1242.400 liv . . 10 1142. 33 Ex .964 .011 11 1043.1 li . . 11 0943.4 liv . . 11 083.667 liv . . 11 073.900 liv . . 11 064.1 li . . 11 054.367 Ex .959 .012 12 044.433 liv . . 12 034.9 Alive . . 2 025.1 Ex .954 .013 3 015.2 liv . . 3 005.6 liv . . 3 1995.867 liv . . 3 1986.1 li . . 3 1976.200 li . . 3 1966.2 li . . 3 1956.400 li . . 3 1946.667 liv . . 3 1936.800 Alive . . 3 1926.833 liv . . 3 1916.900 li . . 3 1906.933 li . . 3 1897.033 liv . . 3 1887.033 liv . . 3 1877.233 Alive . . 3 1867.2 li . . 3 1857.767 li . . 3 1847.867 Alive . . 1838.0 li . . 1828.400 liv . . 818.400 li . . 808.4 liv . . 798.533 Ex .949 .014 4 788.933 liv . . 4 779.533 liv . . 4 769.700 liv . . 4 759. 33 li . . 4 749. 67 li . . 4 7350.767 li . . 4 7250.8 li . . 4 7150.900 li . . 4 7051. liv . . 4 6951. 67 li . . 4 6851.3 liv . . 4 6751.3 liv . . 4 6651. 00 li . . 4 6551.800 li . . 4 6452. li . . 4 6352. 67 liv . . 4 6253.067 li . . 4 6153.200 Alive . . 6053.600 li . . 5954.267 li . . 5854.3 liv . . 5754.300 li . . 5654.600 li . . 554.633 liv . . 545.000 li . . 535.033 li . . 525.800 li . . 515.8 li . . 506.2 Ex .943 .015 5 496.4 li . . 5 486.567 li . . 5 476.567 li . . 5 466.833 li . . 5 456.933 li . . 5 447. 33 liv . . 5 437.067 liv . . 5 427.233 li . . 5 417.600 li . . 5 407.7 li . . 5 397.8 li . . 5 387.833 li . . 5 378.100 li . . 5 368.367 li . . 5 358.700 li . . 5 348. li . . 5 339.000 li . . 5 329.100 Alive . . 319.133 Ex .935 .017 6 309.133 li . . 6 299.233 li . . 6 289.500 li . . 6 279.7 li . . 6 2660.100 li . . 6 2560.1 li . . 6 2460. 67 li . . 6 2361.167 li . . 6 2261.267 li . . 6 2161.367 li . . 6 2061.567 li . . 6 1962.067 li . . 6 1862.233 li . . 6 1762.267 li . . 6 1663.0 li . . 6 1563.433 li . . 6 1463.633 li . . 6 1363.6 Alive . . 1263.667 li . . 1163.800 li . . 1064.1 li . . 0964.367 li . . 084.5 li . . 074.500 li . . 064.933 li . . 055.233 li . . 045.400 li . . 035.833 li . . 026.000 Ex .926 .019 7 016.500 li . . 7 007.6 li . . 7 997.633 li . . 7 987.767 li . . 7 977.9 li . . 7 968.067 li . . 7 958.100 li . . 7 948.200 li . . 7 939.033 li . . 7 929.8 li . . 7 919.9 li . . 7 9070.3 li . . 7 8971.0 li . . 7 8871.1 li . . 7 8771.467 li . . 7 8671.633 li . . 7 8571.9 li . . 7 8473. Alive . . 8373.033 Ex .915 .022 8 8273.0 li . . 8 8173.200 li . . 8 8073.400 li . . 8 7973.6 li . . 8 7874.1 li . . 8 7774.2 li . . 8 7674.433 li . . 8 7574.900 li . . 8 7475.6 li . . 8 7375.633 Ex .902 .025 9 726.0 li . . 9 716.333 li . . 9 706.500 li . . 9 696.633 Ex .889 .028 20 687.200 li . . 20 679.400 li . . 20 6680. li . . 20 6580. 00 Alive . . 20 6480.400 li . . 20 6380.467 Ex .875 .031 21 6280. 67 li . . 21 6180.500 li . . 21 6080.533 li . . 21 5980.7 li . . 21 5880.900 li . . 21 5781.2 li . . 21 5681.367 li . . 21 5582.3 Alive . . 21 5483. 67 li . . 21 5383.067 li . . 21 5283.3 li . . 21 5183. Alive . . 1 5084.433 li . . 1 4986.033 li . . 1 486.567 li . . 1 477.8 li . . 1 469.133 li . . 1 459.300 Alive . . 449.833 li . . 439 .1 li . . 429 .400 li . . 419 .967 li . . 4091.267 li . . 3992.1 li . . 3892.400 li . . 379 .467 li . . 369 .333 li . . 359 .900 li . . 3494.5 li . . 3394.967 li . . 3295.3 li . . 319 .1 li . . 309 . 00 Ex .846 .041 2 2996. 33 li . . 2 2896.8 li . . 2 279 . li . . 2 269 .4 li . . 2 259.6 li . . 2 24101.867 li . . 2 23102.900 li . . 2 22103.567 li . . 2 21104.233 li . . 2 20104.467 li . . 2 19105.467 li . . 2 18106.200 li . . 2 17108.933 li . . 2 16109.867 li . . 2 15109.900 li . . 2 14110.100 li . . 2 13114.067 li . . 2 12117.733 Alive . . 11118.833 li . . 10119.367 li . . 9120.067 li . . 8120.167 li . . 7125.367 li . . 625.400 li . . 527.867 li . . 430.233 li . . 332. li . . 232.6 li . . 133.800 li . . 02.633 Ex .997 .003 1 3673.000 li . . 1 3663.533 li . . 1 3653.567 li . . 1 3643.967 li . . 1 3634.133 li . . 1 3624.13 li . . 1 3614.267 li . . 1 3604.567 li . . 1 3594.867 li . . 1 3584.900 li . . 1 3575.267 li . . 1 3565.30 li . . 1 3 56.100 li . . 1 3546.700 li . . 1 3536.900 li . . 1 3527.033 li . . 1 3517.40 li . . 1 3507.700 Alive . . 497.733 li . . 487.767 li . . 477.833 li . . 467. 00 li . . 458.600 li . . 448.600 li . . 439.300 Ex .994 .004 2 429.4 li . . 2 419.4 li . . 2 409.5 li . . 2 399.533 li . . 2 389.733 li . . 2 379.833 li . . 2 369.9 li . . 2 3510.500 li . . 2 3410.700 li . . 2 3311.067 li . . 2 3211.167 li . . 2 3111.300 li . . 2 3011.433 li . . 2 2911.967 li . . 2 2812.000 Ex .991 .005 3 2712.300 li . . 3 2612.367 li . . 3 2512.567 Alive . . 3 2412.633 li . . 3 2312.767 li . . 3 2212.767 li . . 3 2112.800 li . . 3 2013.067 li . . 3 1913.233 li . . 3 1813.467 li . . 3 173.6 li . . 3 163.667 li . . 3 153.900 li . . 3 144.033 li . . 3 134. li . . 3 124. li . . 3 114.500 li . . 3 104.733 . 88 . 6 4 094.8 li . . 4 084.800 li . . 4 075.333 li . . 4 065. 00 li . . 4 055.833 li . . 4 046.0 li . . 4 036.2 Ex .985 .007 5 026.200 li . . 5 016.3 li . . 5 006.500 li . . 5 2996. 33 li . . 5 2986. li . . 5 2977.033 li . . 5 2967.2 li . . 5 2957.233 li . . 5 2947.300 li . . 5 2937.333 li . . 5 2927.400 Alive . . 5 2917.633 li . . 5 2907.733 li . . 5 2897.800 li . . 5 2888.167 li . . 5 2878.667 li . . 5 2868.800 li . . 5 2858.867 Alive . . 2848.933 li . . 2839. li . . 2829.7 li . . 819.800 li . . 8020.033 li . . 7920.100 li . . 7820. 00 li . . 7720.7 li . . 7621.0 li . . 7521.267 Ex .981 .008 6 7421.6 li . . 6 7321.800 li . . 6 7222.067 li . . 6 7122.3 li . . 6 7022.333 li . . 6 6922.5 li . . 6 6822.667 li . . 6 6722. li . . 6 6622. 67 li . . 6 6523.000 li . . 6 6423.367 li . . 6 6323.4 li . . 6 623.400 li . . 6 613.667 li . . 6 604.7 li . . 6 595.0 li . . 6 585.167 li . . 6 575.3 Alive . . 565.433 li . . 555.633 li . . 545.800 li . . 535.833 li . . 525.967 li . . 516.000 li . . 506.000 li . . 496.1 li . . 486.3 li . . 476.6 Ex .977 .009 7 466.733 li . . 7 456.833 li . . 7 447.133 li . . 7 437.400 Ex .973 .009 8 427.4 li . . 8 417.500 li . . 8 407.7 li . . 8 398.133 li . . 8 388.667 li . . 8 378.9 li . . 8 369.267 Ex .969 .010 9 359.300 li . . 9 349.400 li . . 9 339.9 li . . 9 3230. li . . 9 3130.0 li . . 9 3030.100 li . . 9 2930.233 . 65 . 11 10 2830.5 li . . 10 2730.567 li . . 10 2631.067 li . . 10 2531.233 Alive . . 10 2431.233 li . . 10 2331. li . . 10 2231. 00 li . . 10 2132. 67 li . . 10 2032.200 li . . 10 1932.600 li . . 10 1832.9 Alive . . 10 1733.033 li . . 10 1633. 33 li . . 10 1533.567 li . . 10 144.267 li . . 10 135.100 li . . 10 125. 33 li . . 10 115. Alive . . 105.767 li . . 095.8 li . . 085.900 li . . 075.900 li . . 066.000 li . . 056.3 li . . 046.4 li . . 036.433 li . . 026.933 li . . 017.267 li . . 007.3 li . . 1997.4 li . . 1987.500 li . . 1977.700 li . . 1968. 00 li . . 1958.667 li . . 1948.767 li . . 1938.767 li . . 1928.800 li . . 1918.9 li . . 1909.4 li . . 1899.4 li . . 1889.467 li . . 1879.5 Ex .960 .012 1 18640.1 li . . 1 18540.167 Ex .955 .013 2 18440.267 li . . 2 18340.533 li . . 2 18240.600 li . . 2 8140.7 li . . 2 8040.733 li . . 2 7940.8 li . . 2 7841.033 li . . 2 7741.200 li . . 2 7641.4 Ex .949 .014 3 7541.800 li . . 3 7442.167 li . . 3 7342.1 li . . 3 7242.367 li . . 3 7142. li . . 3 7042. 33 Ex .944 .015 4 6942. 33 Alive . . 4 683.4 li . . 4 673.4 Alive . . 4 663.600 li . . 4 653.700 li . . 4 643.867 li . . 4 634.067 li . . 4 624. 67 li . . 4 614.967 li . . 4 605.467 li . . 4 595.667 li . . 4 585.700 Alive . . 4 575.933 li . . 4 566.433 li . . 4 556.633 li . . 4 546.9 li . . 4 537.067 li . . 4 527.1 Alive . . 517.4 li . . 507.967 Ex .937 .016 5 498. 00 li . . 5 488.467 li . . 5 478. 67 li . . 5 469.233 li . . 5 459.3 li . . 5 449.3 li . . 5 439.4 li . . 5 429.600 li . . 5 419. li . . 5 4050.333 li . . 5 3950.667 Ex .931 .017 6 3850.800 li . . 6 3751.100 li . . 6 3651.4 li . . 6 3551.500 li . . 6 3451.700 li . . 6 3351.700 li . . 6 3251.833 Alive . . 6 3151.967 li . . 6 3052.033 li . . 6 2952.033 li . . 6 2852.1 li . . 6 2752.433 li . . 6 2652.4 li . . 6 2552.700 Ex .923 .019 7 2452.933 li . . 7 2353.000 li . . 7 223.167 li . . 7 213.300 Alive . . 7 203.333 li . . 7 193.367 li . . 7 183.3 li . . 7 173.633 li . . 7 163.867 li . . 7 154.433 li . . 7 145.0 li . . 7 135.633 li . . 7 125.767 li . . 7 115.867 li . . 7 106.0 li . . 7 097. li . . 7 087.8 li . . 7 077.9 Alive . . 068.0 li . . 058.367 li . . 048.433 li . . 038.733 li . . 028.867 li . . 019.400 li . . 009.500 li . . 999.700 li . . 989.733 li . . 979.767 li . . 9660. 67 li . . 9561.100 li . . 9461.1 li . . 9361.900 li . . 9261.967 li . . 9162.2 li . . 9062.4 li . . 8962.5 li . . 8863. li . . 8763.0 li . . 8663.267 li . . 8563.267 li . . 8463.4 li . . 8364.0 li . . 8264.3 li . . 8165.067 li . . 8065.3 li . . 7965.500 li . . 785.6 li . . 776.233 li . . 766.300 li . . 756.6 li . . 746.800 Ex .911 .022 8 737 6 li 8 727 900 li 8 718 167 li 8 708.900 li . . 8 699. 33 li . . 8 689.800 li . . 8 6770.633 li . . 8 6670.733 li . . 8 6570.8 li . . 8 6470.9 li . . 8 6370.9 li . . 8 6271.1 li . . 8 6171 33 li 8 6072 433 li 8 5973 7 li 8 5873.833 li . . 8 5774.1 li . . 8 5674.433 Alive . . 5574.5 li . . 5475.7 li . . 5375.733 li . . 5276.3 li . . 5177 200 li 5077.233 li . . 497 7 li 489 0 li 479 li 469.8 li . . 459.8 li . . 4480. 00 li . . 4380 800 li 4281 900 li 4181 9 Ex .888 .031 9 4082.600 Ex .866 .037 20 3982.933 li . . 20 3882.967 li . . 20 3783 067 li 20 3683 67 li 20 3584 4 li 20 3484.467 li . . 20 3384.733 li . . 20 3285.7 li . . 20 3186 200 li 20 3088.9 li . . 20 298 .033 li . . 20 288 33 li 20 2791 6 li 20 2691 967 li 20 2592 233 li 20 2492 533 li 20 2394 767 Alive . . 20 2295.2 Alive . . 2195 6 li 2097 033 li 1997 7 li 1898 500 li 17100.100 li 16100.733 li 15101.667 li 14103.433 li . . 13105.733 li 12106.300 li 11107.367 li 10110.067 li 9112.433 li . . 8112.867 li . . 7113.267 li 6114.067 li 5117.267 li 4119.867 li 3122.600 li 2129.567 li 1129.733 li 012345678910111213141516171819202122232425262728293031323334353637383940414243444546474849505152535455565758596061626364656667686970717273747576777879808182838485868788899091929394959697989910010110210310410510610710810911011111211311411511611711811912012112212312412512612712812913013113213313413513613713813914014114214314414514614714814915015115215315415515615715815916016116216316416516616716816917017117217317417517617717817918018118218318418518618718818919019119219319419519619719819920020120220320420520620720820921021121221321421521621721821922022122222322422522622722822923023123223323423523623723823924024124224324424524624724824925025125225325425525625725825926026126226326426526626726826927027127227327427527627727827928028128228328428528628728828929029129229329429529629729829930030130230330430530630730830931031131231331431531631731831932032132232332432532632732832933033133233333433533633733833934034134234334434534634734834935035135235335435535635735835936036136236336436536636736836937037137237337437537637737837938038138238338438538638738838939039139239339439539639739839940040140240340440540640740840941041141241341441541612345678910111213141516171819202122232425262728293031323334353637383940414243444546474849505152535455565758596061626364656667686970717273747576777879808182838485868788899091929394959697989910010110210310410510610710810911011111211311411511611711811912021222324252612712812913013113233343536373813914014114214314445464748495015115215315415515657585960616216316416516616716869707172737475761771781791808182838485868788899091192939495969798992002012022032042052062072082092102112122132142152162171819202122232425262728293031323334353637383940414243444546474849505152535455565758596061626364656667686970717273747576777879808182838485868788899091929394959697989930030130230330430530630730830931031131231331431531631718192021222324252627282930313233343536373839404142434445464748495051525354555657585960616263646566676869707172737475767778798081828384858687888990919293949596979899400401402403404405406407408409410411412413414415416417181920212223123567891011213141516171890212223242526272829303132333435363738394041424344454647484950515253545556575859606162636465666768697071727374757677787980818283848586878889909192939495969798991001011021031041051061071 81091101111121131141151161171819202122232425262728293031323334353637383940414243444546474849505152535455565758596061626364656667686970717273747576777879808182838485868788899091929394959697989920020120220320420520620720820921021121221321421521621718192021222324252627282930313233343536373839404142434445464748495051525354555657585960616263646566676869707172737475767778798081828384858687888990919293949596979899300301302303304305306307308309310311312313314315316317181920212223242526272829303132333435363738394041424344454647484950515253545556575859606162636465666768agegr<4950-6465+Time Status Estimate Std. ErrorCumulativeProportion Survivingat the Time N of CumulativeEvents N of Remaining Cases1 yıllık sağkalım (SH):99,7 (0,3)
24Tek-değişkenli ve Eş-değişkenli AnalizOverall Comparisons8.089 2 .018Log Rank(Mantel-Cox)Chi-Square df Sig.Test of equality of survival distributions for the differentlevels of Histologic Grade.Pairwise Comparisons.972 .324 3.926 .048.972 .324 5.714 .0173.926 .048 5.714 .017histgradWellModeratePoorLog Rank(Mantel-Cox)Chi-Square Sig. Chi-Square Sig. Chi-Square Sig.Well Moderate PoorOverall Comparisons7.823 1 .005Log Rank(Mantel-Cox)Chi-Square df Sig.The vector of trend weights is -1, 0, 1. This is the default.LN etkisi?Overall Comparisonsa6.135 1 .013Log Rank(Mantel-Cox)Chi-Square df Sig.The vector of trend weights is -1, 0, 1. This is the default.Adjusted for Lymph Nodes?.a.
A German multicenter, randomized phase IIItrial comparing irinotecan–carboplatin withetoposide–carboplatin as first-line therapy forextensive-disease small-cell lung cancer25Figure. Kaplan–Meier estimates for overall survival by treatment arm.Irinotecan plus carboplatin versus etoposide plus carboplatin.One-year survival was 37.1% (95%CI 26.1% to 48.1%) and 30.3% (95% CI 20.5% to 40.1%) in the X and Y arms (P = 0.36).
26Figure. Kaplan–Meier estimates for progression-free survival by treatment arm.A German multicenter, randomized phase IIItrial comparing irinotecan–carboplatin withetoposide–carboplatin as first-line therapy forextensive-disease small-cell lung cancerOne-year PFS was 11.8% (95% CI 4.2% to 19.4%) in the X arm and 6.5% (95% CI 1.1% to 11.9%) in the Y arm (P = 0.22).
27Çok Değişkenli Sağkalımh(t) = [h0(t)] x e (B x faktör)h(t) = [h0(t)] x e (B1 x faktör1 + B2 x faktör2)Taban risk Ek risk
28Hazard Fonksiyonu Belli bir döneme kadar yaşayan kişinin o dönem boyunca birim zamanda ölme riskini tarif eden bir fonksiyondur. Belli bir süreye kadar olay görülmeyen kişinin o sırada birim zamanda olay görülme riskini tarif eden bir fonksiyondur.
29Hazard Oranı İki grupta görülen hazard fonksiyonlarının birbirine oranıdır. Regresyon modellemesinde (Cox) tüm zamanlar kesitleri için gruplar arasındaki risk farkı (oranı) sabit demektir.
30Hazard
31LML
32Variables in the Equation7.171 2 .028.678 .505 1.801 1 .180 1.969 .732 5.299.930 .357 6.804 1 .009 2.534 1.260 5.097.712 2 .701.723 1.035 .488 1 .485 2.061 .271 15.669.859 1.054 .664 1 .415 2.361 .299 18.648-.074 .428 .030 1 .862 .928 .401 2.149-.489 .424 1.327 1 .249 .613 .267 1.4094.899 2 .086.713 .326 4.770 1 .029 2.039 1.076 3.865-.006 1.036 .000 1 .996 .994 .130 7.582-.016 .013 1.469 1 .226 .984 .958 1.0107.142 2 .028.666 .500 1.770 1 .183 1.946 .730 5.188.926 .356 6.766 1 .009 2.523 1.256 5.069.769 2 .681.725 1.035 .491 1 .484 2.064 .272 15.695.874 1.051 .693 1 .405 2.397 .306 18.792-.530 .351 2.275 1 .131 .589 .296 1.1724.966 2 .083.716 .326 4.822 1 .028 2.046 1.080 3.875-.016 1.035 .000 1 .988 .984 .130 7.480-.017 .013 1.579 1 .209 .983 .958 1.0098.104 2 .017.678 .500 1.837 1 .175 1.970 .739 5.249.976 .350 7.757 1 .005 2.654 1.335 5.275-.598 .337 3.155 1 .076 .550 .284 1.0645.706 2 .058.763 .323 5.570 1 .018 2.145 1.138 4.044.016 1.031 .000 1 .988 1.016 .135 7.670-.018 .013 1.802 1 .179 .982 .957 1.00810.494 2 .005.724 .499 2.105 1 .147 2.063 .776 5.4891.087 .342 10.125 1 .001 2.966 1.518 5.794-.722 .326 4.905 1 .027 .486 .256 .9207.328 2 .026.853 .317 7.230 1 .007 2.346 1.260 4.369.108 1.030 .011 1 .917 1.114 .148 8.394lngrlngr(1)lngr(2)histgradhistgrad(1)histgrad(2)erprtumsize2tumsize2(1)tumsize2(2)ageStep1lngrlngr(1)lngr(2)histgradhistgrad(1)histgrad(2)prtumsize2tumsize2(1)tumsize2(2)ageStep2lngrlngr(1)lngr(2)prtumsize2tumsize2(1)tumsize2(2)ageStep3lngrlngr(1)lngr(2)prtumsize2tumsize2(1)tumsize2(2)Step4B SE Wald df Sig. Exp(B) Lower Upper95.0% CI for Exp(B)HR: 2.96 (95%CI:1.52-5.80), p:0.001